Cortisol levels can also be affected by low sodium, so adding a bit of sea salt during the day might help. Dr. Berg also noted that the liver is most active between 1 and 3 a.m., so waking then could suggest liver strain, with milk thistle sometimes offering support. In that sense, sleep may be sending important signals about what’s going on in the body.

When it comes to people over 60 especially, waking up at this time during the night can signal underlying health issues.

1. A natural drop in melatonin

When people who reach certain age start waking up at 3 a.m., it doesn’t necessarily mean they experience issues with stress or poor sleep habit. On the contrary, one of the main reasons for waking up at this time, is the natural reduction of melatonin, which is the hormone that regulates your sleep-wake cycle.

When you are younger, your melatonin levels remain high throughout the night, which helps you sleep deep. However, as you age, your body produces less melatonin. By the early morning hours, your melatonin levels may be low enough to trigger your brain to wake up, even if you have not slept as long as you wanted or needed.