Scientists at McGill University have uncovered a molecular mechanism explaining vitamin D’s potential role in protecting against cancer. Their research shows that the active form of vitamin D inhibits the growth of cancer cells. Additionally, individuals with higher blood levels of vitamin D tend to have significantly longer lifespans compared to those with lower levels.
Led by Professors John White and David Goltzman from the Department of Physiology, the team discovered that active vitamin D suppresses both the production and activity of the cancer-promoting protein cMYC through various pathways. This protein drives excessive cell division and is overexpressed in more than half of all human cancers. The findings were published in the Proceedings of the National Academy of Sciences.
In recent years, growing attention has focused on vitamin D’s potential benefits for overall health and preventing diseases. Previous studies have linked vitamin D deficiency to higher risks of various cancers and cardiovascular conditions. Stephen B. Kritchevsky, PhD, a professor at Wake Forest School of Medicine, highlighted a clear association between low vitamin D levels and increased mortality.