Recent studies indicate that this biological trait—often overlooked outside of transfusions or medical emergencies—could have a bigger role than we think in how our cells age.
Why People With Blood Type O May Have Certain Advantages
According to some preliminary findings, people with blood type O may have certain natural long-term health advantages. This group, which is the most common worldwide, has been linked to a lower likelihood of developing cardiovascular issues such as heart attacks or strokes, as well as a reduced risk of certain types of cancer.
Their blood clotting system also tends to function more efficiently, which may support better circulation—and therefore better oxygenation of tissues—as the body ages.

The Challenges Faced by Blood Types A, B, and AB
By contrast, people with blood types A, B, or AB could face additional challenges as they get older. Some research has connected these groups to higher levels of chronic inflammation, a key contributor to physical decline over time.